Posts Tagged ‘sensitivity’
Infant Pain, Adult Repercussions: How Infant Pain Changes Sensitivity In Adults
Scientists have uncovered the mechanisms of how pain in infancy alters how the brain processes pain in adulthood. Research is now indicating that infants who spent time in the neonatal intensive care unit show altered pain sensitivity in adolescence. These results have profound implications and highlight the need for pre-emptive and post-operative pain medicine for newborn infants.
Researchers Explore Mechanisms Of How Infant Pain Changes Sensitivity In Adults
Scientists at Georgia State University have uncovered the mechanisms of how pain in infancy alters how the brain processes pain in adulthood. Research is now indicating that infants who spent time in the neonatal intensive care unit (NICU) show altered pain sensitivity in adolescence. These results have profound implications and highlight the need for pre-emptive and post-operative pain medicine for newborn infants.
Meridian Granted Special 510(k) Clearance To Add 2009 H1N1 Influenza A Virus Analytical Sensitivity Claim To The TRU FLU(R) Test Package Insert
Meridian Bioscience, Inc., Cincinnati, Ohio (NASDAQ:VIVO) announced that the company has been granted a Special 510(k) clearance to update the TRU FLU package insert to include analytical sensitivity claims with two strains of 2009 H1N1 virus cultured from positive respiratory specimens. TRU FLU is a rapid test which identifies influenza A and B in human specimens.
Genetic Region Controlling Cardiovascular Sensitivity To Anesthetic Propofol Discovered
Researchers at The Medical College of Wisconsin in Milwaukee have identified the genetic region in rats responsible for cardiovascular collapse during anesthesia. While it is well known that people have different cardiovascular sensitivity to anesthesia causing some to collapse even when low doses are administered, the mechanism responsible for this susceptibility is not clear.
Abrupt Opioid Withdrawal Increases Pain Sensitivity
The abrupt withdrawal of morphine-like analgesics – opioids – can increase sensitivity to pain. Experiments have now shown that this effect is caused by a memory-like process, the long-term potentiation of synaptic strength in the spinal cord. The study, which was supported by the Austrian Science Fund FWF, also found ways of avoiding this increase in pain sensitivity. These pioneering results have now been published in the prestigious journal Science.
Study Offers New Insights Into Morphine-Induced Tolerance And Increased Pain Sensitivity
A study published in the June issue of Anesthesiology has shown that a drug metabolite of the opioid morphine may be a key factor in the paradoxical increased sensitivity to pain caused by chronic morphine use. For the first time, this metabolite (called morphine-6 glucuronide, or M6G) was shown to act independently of the pain receptors typically targeted during morphine administration. The study, which was led by Albert Dahan, M.D., Ph.D.
Pain Sensitivity Increases With Opioids Treatment
Use of opioid pain medications may contribute to an increase in sensitivity to some types of pain, according to an Australian study published in The Journal of Pain. Researchers sought to examine the effect of long-term opioid use in chronic noncancer pain patients and opioid-maintained patients to determine if the medications can cause hyperalgesia or allydonia.
Area Twins Needed For Pain Sensitivity Study
SRI International, an independent, nonprofit research and development institute, is seeking healthy fraternal and identical twin pairs to participate in a National Institutes of Health-sponsored study that will help scientists develop more targeted and effective pain relief medications. Volunteer twins will participate in one day of tests at Stanford University School of Medicine.
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