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Posts Tagged ‘mechanism’

Cellular Mechanism That Causes Lupus-like Symptoms In Mice Identified

Macrophages, the scavenger cells of the body’s immune system, are responsible for disposing of dying cells. Researchers have identified one pathway in this important process in mice that, if disrupted, causes a lupus-like autoimmune disease.

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Study Pinpoints Key Mechanism In Brain Development, Raising Question About Use Of Antiseizure Drug

Researchers at the Stanford University School of Medicine have identified a key molecular player in guiding the formation of synapses – the all-important connections between nerve cells – in the brain. This discovery, based on experiments in cell culture and in mice, could advance scientists’ understanding of how young children’s brains develop as well as point to new approaches toward countering brain disorders in adults.

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Key Mechanism In Brain Development Pinpointed, Raising Question About Use Of Antiseizure Drug

Researchers have identified a key molecular player in guiding the formation of synapses — the all-important connections between nerve cells — in the brain. This discovery, based on experiments in cell culture and in mice, could advance scientists’ understanding of how young children’s brains develop as well as point to new approaches toward countering brain disorders in adults.

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Funxional Successfully Completes Initial Clinical Trial Of FX125L, An Anti-Inflammatory Drug With A Novel Mechanism Of Action

Funxional Therapeutics Ltd (Funxional) has announced the successful completion of the first Phase I study with FX125L, an orally available small molecule which belongs to a new therapeutic class named Broad Spectrum Chemokine Inhibitors (BSCIs). The Phase I, single ascending dose study was conducted in the United States. FX125L was well tolerated at all doses studied and no serious adverse events or subject withdrawals were observed.

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USC Researchers Uncover Mechanism That Allows Influenza Virus To Evade The Body¹s Immune Response

California (USC) have identified a critical molecular mechanism that allows the influenza virus to evade the body¹s immune response system. The study will be published in the May 21 issue of the journal Cell Host & Microbe. ³We have found a mechanism that the influenza virus uses to inhibit the body¹s immune response that emphasizes the vital role of a specific protein in defending against viruses,” says Jae Jung, Ph.D.

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Discovery Of Mechanism That Processes ‘THC’ Type Brain Compound May Lead To New Medicines For Pain, Addiction

Scientists have discovered a new molecular mechanism for the processing of endocannabinoids, brain compounds similar to THC, the active ingredient in marijuana, and essential in physiological processes such as pain, appetite, and memory.

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Discovery Of Mechanism That Processes A “THC” Type Brain Compound May Lead To New Medicines For Pain, Addiction

Dale Deutsch, Ph.D., Professor of Biochemistry and Cell Biology at Stony Brook University and colleagues discovered a new molecular mechanism for the processing of endocannabinoids, brain compounds similar to THC, the active ingredient in marijuana, and essential in physiological processes such as pain, appetite, and memory.

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Discovery Of Mechanism That Processes A ‘THC’ Type Brain Compound May Lead To New Medicines For Pain, Addiction

Scientists have discovered a new molecular mechanism for the processing of endocannabinoids, brain compounds similar to THC, the active ingredient in marijuana, and essential in physiological processes such as pain, appetite, and memory.

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Hot Chili Peppers Help Unravel The Mechanism Of Pain

Capsaicin, the active ingredient in spicy hot chili peppers such as the jalapeno, is most often experienced as an irritant, but it may also be used to reduce pain. New research uses capsaicin to uncover novel insight into how pain-receptor systems can adapt to painful stimuli.

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Chili Peppers Help To Unravel The Mechanism Of Pain

Capsaicin, the active ingredient in chili peppers, is most often experienced as an irritant, but it may also be used to reduce pain. A new work published by Drs. Feng Qin and Jing Yao in this week’s PLoS Biology uses capsaicin to uncover novel insight into how pain-receptor systems can adapt to painful stimuli. Sensory systems are well known to adapt to prevailing stimuli.

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