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Posts Tagged ‘insights’

Study Offers New Insights Into Morphine-Induced Tolerance And Increased Pain Sensitivity

A study published in the June issue of Anesthesiology has shown that a drug metabolite of the opioid morphine may be a key factor in the paradoxical increased sensitivity to pain caused by chronic morphine use. For the first time, this metabolite (called morphine-6 glucuronide, or M6G) was shown to act independently of the pain receptors typically targeted during morphine administration. The study, which was led by Albert Dahan, M.D., Ph.D.

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Rat Model Provides Insights Into Sciatica

A newly developed animal model for the painful nerve condition known as sciatica should help researchers diagnose and treat it, according to Duke University bioengineers and surgeons. Sciatica is not a single disorder, but rather a diverse range of symptoms, such as numbness or pain from the lower back to the feet, radiating leg pain or difficulty in controlling the leg.

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FDA Researchers Contribute Insights Into Avian Flu Virus

An in-depth analysis of blood from patients recovering from the H5N1 avian influenza virus has provided important insights into how to combat the potentially lethal virus. The findings by U.S. Food and Drug Administration scientists and collaborators better explain what part of the “bird flu” virus is seen by the immune system once a person becomes infected.

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Addiction: Insights From Parkinson’s Disease

A new comprehensive review provides vital insights into the neurological basis of addiction by investigating Parkinson’s disease patients, who in some instances develop various addictions when undergoing medical treatment. The review illustrates that persistently elevated levels of dopamine in the brain promote the development and maintenance of addictive behaviors.

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