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Posts Tagged ‘effects’

Prozac and Celexa exhibit anti-inflammatory effects

A new study found that fluoxetine (Prozac) and citalopram (Celexa) treatment significantly inhibited disease progression of collagen-induced arthritis in mice. Researchers studied the anti-arthritic potential of these drugs, known as selective serotonin reuptake inhibitors most commonly used to treat depression.

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Interviewer effects in public health surveys

Interviewer effects can have a substantial impact on survey data and may be particularly operant in public health surveys, where respondents are likely to be queried about racial attitudes, sensitive behaviors and other topics prone to socially desirable responding. This paper defines interviewer effects, argues for the importance of measuring and controlling for interviewer effects in health surveys, provides advice about how to interpret research on interviewer effects and summarizes research to date on race, ethnicity and gender effects. Interviewer effects appear to be most likely to occur when survey items query attitudes about sociodemographic characteristics or respondents’ engagement in sensitive behaviors such as substance use. However, there is surprisingly little evidence to indicate whether sociodemographic interviewer–respondent matching improves survey response rates or data validity, and the use of a matched design introduces possible measurement bias across studies. Additional research is needed to elucidate many issues, including the influence of interviewers’ sociodemographic characteristics on health-related topics, the role of within-group interviewer variability on survey data and the simultaneous impact of multiple interviewer characteristics. The findings of such research would provide much-needed guidance to public health professionals on whether or not to match interviewers and respondents on key sociodemographic characteristics.

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Side Effects Of Stereotactic Body Radiation Therapy In Lung Cancer Patients Significantly Increased By Obesity

Obesity, not the amount of radiation given, is the greatest factor in whether early-stage lung cancer patients develop chest wall pain after receiving stereotactic body radiation therapy to the chest wall, with obese patients being more than twice as likely to develop chronic pain compared to those who have less body weight, according to a first-of-its-kind study presented Tuesday, November 3, 2009, at the 51st Annual Meeting of the American Society for Radiation Oncology (ASTRO).

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Study Assesses Pain Drug Side Effects

A new study reports the side effects of oxycodone, a widely used opioid pain medication, are similar in healthy older adults as in younger age groups, therefore, clinicians should not shy away from prescribing the drug to relieve pain in older patients. The article appears in The Journal of Pain, the peer review publication of the American Pain Society.

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Effects Of Aspirin And Folic Acid On Inflammation Markers For Colorectal Adenomas

Unexpectedly, inflammation markers do not appear to be involved with the chemopreventative effect of aspirin on colorectal adenomas, according to a brief communication published online October 12 in the Journal of the National Cancer Institute. Aspirin has been shown to prevent the recurrence of colorectal polyps, but it’s not clear how it works.

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Strategies For Reducing Painful Breast Cancer Drug Side Effects

New research has identified patterns that may help breast cancer patients at risk of serious joint pain from aromatase inhibitors. In a recent study, researchers found that estrogen withdrawal may play a role in the onset of arthralgia during treatment: Women who stopped getting their menstrual periods less than five years before starting breast cancer treatment were three times more likely to experience these pains than those who reached menopause earlier.

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Effects Of Chemotherapy Drugs Unravelled By Yeast

Until now, the mode of action of nitrogen-containing bisphosphonate (N-BP) cancer drugs, used to relieve bone pain and to prevent skeletal complications in bone metastasis, has been almost entirely unknown. Researchers writing in BioMed Central’s open access journal Genome Biology have used ‘barcoded’ yeast mutants to identify new biological processes involved in the cellular response to N-BPs, opening up opportunities for the development of new anticancer drugs.

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Yeast Unravels Effects Of Chemotherapy Drugs

Until now, the mode of action of nitrogen-containing bisphosphonate (N-BP) cancer drugs, used to relieve bone pain and to prevent skeletal complications in bone metastasis, has been almost entirely unknown. Researchers have used “barcoded” yeast mutants to identify new biological processes involved in the cellular response to N-BPs, opening up opportunities for the development of new anticancer drugs.

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Electroacupuncture Shows Effects On Pain Perception

Experiments in volunteers confirm that electroacupuncture applying electrical current to acupuncture needles has pain-reducing effects, reports a study in the September issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS). The results also lend new insights into how long treatments should be for greatest effectiveness.

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MOC-Etomidate: Retaining Beneficial Anesthetic Properties, Reducing Dangerous Side Effects

Researchers at Massachusetts General Hospital (MGH) have developed a new anesthetic agent, which they think could be a breakthrough in the quest to discover drugs that retain beneficial anesthetic properties while reducing unwanted and occasionally dangerous side effects. Douglas E. Raines, M.D., and his colleagues from the MGH Department of Anesthesia, Critical Care and Pain Medicine believe that the new drug, MOC-etomidate, could prove to be beneficial for many surgical patients.

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