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Sickle Cell Pain May Be From Damaged Tissues Or Nerves

Researchers at the University of Illinois at Chicago have discovered the pain caused by sickle cell disease may not occur solely from damaged tissues, but also from injured nerves. The research is published in the Journal of the National Medical Association. Sickle cell disease is a hereditary disorder where red blood cells change from round to a sickle shape…

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Bharat Biotech Begins Phase I Clinical Trials Of HN-VAC – Its Cell Culture H1N1 Vaccine

Bharat Biotech today announced that it has commenced Phase I clinical evaluation of HN-VAC, its cell culture based H1N1 vaccine candidate. Bharat Biotech received the nod from Drugs Controller General of India (DCGI) to conduct the Phase I clinical trials…

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New Insight Into Nerve Cell Communication

Communication between nerve cells is vital for our bodies to function. Part of this communication happens through vesicles containing signalling molecules called neurotransmitters. The vesicle fuses with the nerve cell membrane; the neurotransmitters are released and quickly recorded by the next nerve cell…

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New insight in nerve cell communication

New nano research gives important insights in nerve cell communication that will help the fight against nerve pain following amputation and diabetes. Researchers have studied, with nanotechnology techniques, the way proteins recognize the small membrane vesicles that transmit signaling molecules from one nerve cell to another.

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Barriers To Pain Treatment In Children With Sickle Cell Disease Revealed By New Study

A new study by researchers from the Medical College of Wisconsin, in Milwaukee, found a substantial variation in hydroxyurea utilization for pain and other sickle cell disease complications in children. Barriers to its use on the part of both providers and patients were also identified. The study led by Amanda M…

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H1N1 more risky than seasonal flu in children with sickle cell disease

Infection with the H1N1 virus, or swine flu, causes more life-threatening complications than seasonal flu in children with sickle cell disease, according to new research. The findings warn parents and caregivers that such children are more likely to need emergency treatment and stays in an intensive-care unit.

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Endothelin Receptor May Play Role In Sickle Cell Pain

Agonizing physical pain, known as vaso-occlusive pain, can afflict children who have sickle cell disease (SCD). In some cases infants as young as two months of age suffer vaso-occlusive pain so severe that opiate medications and hospitalizations are their only relief. Researchers believe vaso-occlusion is caused by a blockage of the blood vessels that occurs when sickle shaped red cells attempt to pass through the round blood vessels.

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Massage Therapy Helps Manage Pain In Children With Sickle Cell Disease

Massage offers both physical and psychological benefits and is used at Nationwide Children’s Hospital in many areas including Rehabilitation, Physical Medicine and in patients who have received organ transplants, just to name a few. Researchers at Nationwide Children’s recently published a study in the Journal of Pediatric Psychology that revealed the benefits of massage in reducing pain, anxiety and depression in children with Sickle Cell Disease.

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Study Of Pulmonary Hypertension Treatment In Sickle Cell Patients Stopped Early Due To Safety Concerns

The National Heart, Lung and Blood Institute of the NIH has stopped a clinical trial testing a drug treatment for pulmonary hypertension in adults with sickle cell disease nearly one year early due to safety concerns. In an interim review of safety data, researchers found that participants taking sildenafil (Revatio) were significantly more likely to have serious medical problems. The most common problem was episodes of severe pain called sickle cell crises. No deaths have been associated with the drug in the clinical trial.

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Study Of Pulmonary Hypertension Treatment In Sickle Cell Patients Halted By NHLBI

The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health has stopped a clinical trial testing a drug treatment for pulmonary hypertension in adults with sickle cell disease nearly one year early due to safety concerns.

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