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Pandemic Hybrid Of Bird And Human Seasonal Flu Possible Say Scientists

An international team of scientists has created a highly pathogenic laboratory hybrid of the H5N1 bird flu and human seasonal flu viruses by swapping just one gene, and propose that a similar genetic interaction could happen in nature between the current pandemic H1N1 swine flu and H5N1 avian flu strains, highlighting the importance of continued surveillance…

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Virus Hybridization Could Create Pandemic Bird Flu

Genetic interactions between avian H5N1 influenza and human seasonal influenza viruses have the potential to create hybrid strains combining the virulence of bird flu with the pandemic ability of H1N1, according to a new study. In laboratory experiments in mice, a single gene segment from a human seasonal flu virus, H3N2, was able to convert the avian H5N1 virus into a highly pathogenic form…

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Adapting To A New Host: Bird Flu Leaves The Nest

Current research suggests that viral polymerase may provide a new therapeutic target for host-adapted avian influenza. The related report by Gabriel et al, “Spread of Infection and Lymphocyte Depletion in Mice Depends on Polymerase of Influenza Virus” appears in the September 2009 issue of the American Journal of Pathology. Highly pathogenic avian influenza, commonly known as bird flu, is a strain of the influenza virus that has adapted to infect birds.

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Over 15,510 Bird Flu A(H1N1) Human Cases Confirmed Worldwide, Including 99 Deaths

The WHO (World Health Organization) reported yesterday evening that the total number of swine flu A(H1N1) confirmed human cases of infection has exceeded 15,510, including 99 deaths. The real figure is higher because there is a delay between local health authority reports and the WHO global report. The A(H1N1) influenza virus is nowhere near as virulent (aggressive, dangerous) as was originally feared. Experts say it is not more deadly than normal seasonal human influenza.

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Bird Flu Virus Remains Infectious Up To 600 Days In Municipal Landfills

Amid concerns about a pandemic of swine flu, researchers from Nebraska report for the first time that poultry carcasses infected with another threat – the “bird flu” virus – can remain infectious in municipal landfills for almost 2 years. Their report is scheduled for the June 15 issue of ACS’ semi-monthly journal Environmental Science & Technology. Shannon L.

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Bird Flu Research Could Help With Swine Flu Vaccine

A study published this week in the Proceedings of the National Academy of Sciences of the United States of America shows that Aflunov?, the Novartis investigational pre-pandemic avian influenza vaccine formulated with Novartis’ proprietary MF59? adjuvant, can elicit a broadly cross-reactive immune response covering all known H5N1 antigenic variants, even when that booster dose is administered six years after the initial priming dose.

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Technology Could Improve Vaccines For Both Seasonal Flu And Bird Flu

A new computerized method of testing could help world health officials better identify flu vaccines that are effective against multiple strains of the disease. Rice University scientists who created the method say tests of data from bird flu and seasonal flu outbreaks suggest their method can better gauge the efficacy of proposed vaccines than can tests used today.

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Potential Human Vaccine Against Bird Flu

A vaccine to protect humans from a bird flu pandemic is within reach after a new discovery by researchers at the University of Melbourne, Australia The discovery, published in the prestigious Proceedings of the National Academy of Sciences, reveals how boosting T cell immunity could better protect humans from a bird flu pandemic.

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